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Menopausal Syndrome



Menopausal Syndrome is the group of symptoms that sometimes appear in the time before, during and after the normal cessation of menstruation in women at the appropriate age (40–59 years of age being common). The Menopausal period is often associated with the period of time 5 years before and after the cessation of Menstruation.

Symptoms may include hot flushes, night sweats, anxiety, depression, mood swings, insomnia, lethargy and lack of sex drive. Some women may have various symptoms associated with this 'change in life', including Urinary dysfunction, digestive symptoms, palpitations, Joint pains, Headaches etc.

It is interesting to note that in all medicine traditions, a time for the cessation of menstruation was acknowledged, but there were never symptoms associated with it. The fact that many women from Traditional cultures tend to have either no symptoms or very mild symptoms would suggest that modern western diet and lifestyle is largely to blame. This is also evidenced by the fact that a primary formula for Menopause in TCM (Er Xian Tang) was written in the 1950's.


Differential Diagnosis:
1. Yin Deficiency:

Lower back and knee pain, dizziness, tinnitus, night sweats, hot flushes, feet hot at night, insomnia, dry mouth, nocturnal urination
Formulas:
–Cooling Pearl Powder (Diamargaritum)
–Liu Wei Di Huang Wan, standard for Yin deficiency, marked by sore and painful lower back and knees, nocturnal enuresis, dry mouth and mild sweating or flushes.
–Tian Wang Bu Xin Dan: Heart Yin deficiency with Insomnia, irritability, palpitation, poor memory, red and dry tongue with a thin and rapid pulse.

2. Yin and Yang Deficiency with Rising Heat
Sore and weak lower back and knees, dizziness, insomnia, sweating, hot flushes, nervousness or irritable, palpitations, depression, frequent urination
Formulas:
–Cooling Pearl Powder (Diamargaritum)
–Zhi Bai Di Huang Wan: for Yin deficiency with deficient Heat or rising Yang.
–Er Xian Tang: stronger to Warm the Yang while settling 'floating' heat or lowering rising (unsecured) Yang.
–Dan Zhi Xiao Yao San: supports Liver and Spleen, moves Qi and clears deficient Heat. Good for irritability, anger, headache and Liver-heat symptoms. It can be combined with Liu Wei Di Huang Wan or Zhi Bai Di Huang Wan.
–Da Bu Yin Wan: strong to Nourish Yin and clear deficient Heat. For more severe Yin deficiency.

Taiwanese database was studied for trends of Herbs and Formulas prescribed for Menopause throughout the nation (15486 subjects with 54456 prescriptions), the most commonly prescribed medicines were:
  • Dan Zhi Xiao Yao San was the most commonly prescribed formula for Menopause.
  • Er Zhi Wan (Eclipta Han Lian Cao and Ligustrum Nu Zhen Zi) were commonly prescribed.
  • Dan Zhi Xiao Yao San was often combined with Er Zhi Wan or Salvia Dan Shen
  • Zhi Bai Di Huang Wan was also commonly prescribed (usually with Dan Zhi Xiao Yao San)
Click here to see the research


Kun Bao Wan
Kun Bao Wan is a special medicine for menopause and is produced by Beijing Tong Ren Tang:

          Paeoniae Bai Shao 8.25%;
          Mother of Pearl shell 8.25%
          Spatholobus Ji Xue Teng 8.25%;

          Eclipta Han Lian Cao 5.5%;
          Ligustrum Nu Zhen Zi 4.13%;
          Paeonia Chi Shao 4.13%;
          Rehmannia Shu Di Huang 4.13%;
          Scutellaria Huang Qin 4.13%;

          Chrysanthemum Ju Hua 4.13%;
          Adenophonra Sha Shen 4.13%;
          Cynancumi Bai Wei 4.13%;

          Anemarrhena Zhi Mu 4.13%;
Dendrobium Shi Hu 4.13%;
Lycium bark (Di Gu Pi) 4.13%;
Raspberry fruit (Fu Pen Zi) 2.75%;
Dang Gui 2.75%;
Dodder seed (Tu Si Zi) 2.75%;

Lycium Gou Qi Zi 2.75%;
Mulberry leaf (Sang Ye) 2.75%;
Polygonum He Shou Wu 2.75%;
Ophiopogon Mai Men Dong 2.75%
Turtle shell gelatin Gui Ban Jiao
2.06%
Zizyphus seed (Suan Zao Ren) 1.38%;

Honey 5.76%
This formula (along with acupuncture) was as effective as Hormone Replacement Therapy in clinical studies.

The Following Medicines have shown clinical efficacy in relieving Hot Flashes of Menopause (see research)
Soy
Evening Primrose oil
Flaxseed
Saffron

St. Johns wort
Aniseed
Black Cohosh
Licorice
Red Clover
Sage
Valerian

Western Tradition

Simples
Sage
Hops
St. Johns wort
Agnus Castus
Pearl
Rose
Red Clover
Saffron
Licorice


Compounds

Cordial Decoction
Styptic Decoction
Syrup of Dried Roses Simple
Syrup of Hops
Syrup of Water Lillies
Syrup of Agnus Castus
Syrup of Mugwort Compound
Tincture of Balm
Tincture of Dried Rose
Tincture of Sage
Sugar Penids
Sugar Penids with Spices
New Rose Powder (Rosata Nouvelle) (Nicholas)
Abbots Confect of Rose (Diarrhodon Abbatis) (Nicholas)
Aromatic Rose Compound (Aromaticum Rosatum)
Cooling Pearl Powder (Diamargariton Frigidum)
Cooling Powder of Gems
Conserve of Rose
Troches of Agnus Castus
Electuary of Orchid (Diasatyrion)

Rolled Turquoise 13 (Gyu dri 13) (Tibetan Medicine)


Yin Deficiency

Cooling Pearl Powder (Diamargariton Frigidum)
Tragacanth Cooling Powder (Diatragacanth Frigidum)
Electuary to Restore Humidity (Arnold de Villa Nova)


Yang Deficiency

Gelatin of Deer Horn
Tincture of Cinnamon
Electuary of Orchid (Diasatyrion)


Yin and Yang Deficiency

Restorative of Nicholas (Pleres Arconticon)


Yin Deficient Heat

Syrup of Hops
Tincture of Dried Rose
New Rose Powder (Rosata Nouvelle) (Nicholas)
Conserve of Rose
Troches of Sandalwood (Mesue)
Aromatic Rose Compound (Aromaticum Rosatum)
Cooling Pearl Powder (Diamargariton Frigidum)

TCM Classification

Qi Stagnation with Heat
early stages of Menopause, recently ceased menstruation, maybe spotting, depressed, emotional, flushing when irritable

Dan Zhi Xiao Yao San


Yin Deficiency
hot flushes, dizziness, tinnitus, night sweats, palms and soles feel hot, back pain, dry mouth, dry skin, constipation.

Liu Wei Di Huang Wan
Zhi Bai Di Huang Wan
Zuo Gui Yin


Yang Deficiency
hot flushes with cold hands and feet, night sweats, pale face, back pain, depression, feels cold, edema.

Li Zhong Wan
You Gui Wan
Shen Qi Wan (Jin Gui Shen Qi Wan) (Rehmannia 8)


Yin and Yang Deficiency
hot flushes, back pain, night sweats, frequent pale urination, irritable, feels cold, dry throat, dizziness, tinnitus.

Er Xian Tang
Shen Qi Wan (Jin Gui Shen Qi Wan) (Rehmannia 8)


Yin Deficient Heat
Flushes, night sweats, fever or feels hot especially at night, red cheeks, dry mouth, cracked lips, cracked tongue, irritable, insomnia

Dang Gui Liu Huang Tang
Zhi Bai Di Huang Wan


Kidney and Heart not Balanced
hot flushes, palpitations, nigh sweats, anxiety, restlessness, dizziness, tinnitus, excess worry, insomnia

Gan Mai Da Zao Tang
Tian Wan Bu Xin Wan
Liu Wei Di Huang Wan
Zhi Bai Di Huang Wan


Blood Stagnation
flushes, history of painful periods with dark clotted blood, abdominal pain, dull or cyanotic finger nails and lips, dull or dark complexion, choppy pulse

Dang Gui Shao Yao San
Shao Fu Zhu Yu Tang


Special Formulas:

1. Tribulus, Ginger, Saffron, Cinnamon (proven effect, see research below)


Research:
1. Estrogenic Plants: to Prevent Neurodegeneration and Memory Loss and Other Symptoms in Women After Menopause
2. Effect of Tribulus terrestris, ginger, saffron, and Cinnamomum on menopausal symptoms: a randomised, placebo-controlled clinical trial.
3. Efficacy of Crocus sativus (saffron) in treatment of major depressive disorder associated with post-menopausal hot flashes: a double-blind, randomized, placebo-controlled trial.

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