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Liver Cancer

Western Tradition
Simples
Agrimony
Celandine
Bitter Almond
Black Nightshade
Andrographis

Dandelion
Costus
Rhubarb
Turmeric
Withania

Formulas
Decoction of Dodder of Thyme (Mesue)
Decoction for Cancer (Model Botanic Guide)
Syrup of Dodder of Thyme (Mesue)
Syrup of Fumitory Greater
Syrup of Fumitory Compound (Augustana)
Arab Confect Purging Melancholy (Confect Hamech)
Indian Pills (Mesue)


Chinese Classification
Simples
Trichosanthes Tian Hua Fen
Coptis Huang Lian
Ganoderma Ling Zhi
Inonotus (Chaga)

Nux Vomica (Ma Qian Zi)
Rabdosia Dong Ling Cao
Scutellaria Ban Zhi Lian
Lentinula (Shiitake)
Phellinus

Cantharides (Ban Mao)

Formulas






Special Formula

Yanggan Jiedu Sanjie
    Ligustrum Nu zhen zi 12 g,
    Duchesnea indica She Mei 15 g,
    Solanum nigrum Long Kui 15 g,
    Scutellaria barbata Ban Zhi Lian 30 g,
    Euphorbia helioscopia Ze Qi 15 g,
    Ranunculus ternatus root Mao Zhua Cao 15 g,
    Curcuma Yu Jin 15 g
    Polygonum cuspidatum root Hu Zhang 15 g
This formula has been created specifically for Liver cancer and has proven efficacy against Liver Cancer cells and to stop metastasis of Liver Cancer.


Gan Ji Formula
    Codonopsis Dang Shen
    Atractylodes Bai Zhu
    Imperata Bai Mao Gen
    Oyster shell (Mu Li)
    Soft-shelled Turtle Shell (Bie Jia)
    Aconitum gymnandrum Ze Lan
    Citrus Chen Pi
    Ranunculus ternatus Mao Zhua Cao 
    Abrus cantonensis Ji Gu Cao
    Hedyotis Bai Hua She She Cao
    Solanum lyratum Bai Ying
    Scutellaria barbata Ban Zhi Lian
    Ficus pumila Bi Li Guo
    Actinidia arguta Teng Li Gen
This has been used for early stage primary Liver Cancer. When combined with surgery, it improved survival rate. (See here)



Research
Andrographis
–In vivo inhibitory activity of andrographolide derivative ADN-9 against liver cancer and its mechanisms involved in inhibition of tumor angiogenesis.

Cannabis
–Preclinical and Clinical Assessment of Cannabinoids as Anti-Cancer Agents
–Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy
Crocus
–Saffron carotenoids inhibit STAT3 activation and promote apoptotic progression in IL-6-stimulated liver cancer cells.
Lycium Gou Qi Zi
–In Vitro Protective Effects of Lycium barbarum Berries Cultivated in Umbria (Italy) on Human Hepatocellular Carcinoma Cells.
–Composition of Lycium barbarum polysaccharides and their apoptosis-inducing effect on human hepatoma SMMC-7721 cells.
Rheum
–Apoptosis induction in MDA-MB-435S, Hep3B and PC-3 cell lines by Rheum emodi rhizome extracts.
Salvia Dan Shen
–A network pharmacology-based study on the anti-hepatoma effect of Radix Salviae Miltiorrhizae

Saussurea, Mu Xiang
–Volatile oil from Saussurea lappa exerts antitumor efficacy by inhibiting epithelial growth factor receptor tyrosine kinase-mediated signaling pathway in hepatocellular carcinoma.
–Dehydrocostuslactone, a medicinal plant-derived sesquiterpene lactone, induces apoptosis coupled to endoplasmic reticulum stress in liver cancer cells.
–Active compounds from Saussurea lappa Clarks that suppress hepatitis B virus surface antigen gene expression in human hepatoma cells.
Shilajit
–Mineral pitch induces apoptosis and inhibits proliferation via modulating reactive oxygen species in hepatic cancer cells.

Solanum nigrum
–
Cytotoxicity of hydro-alcoholic extracts of Cucurbitapepo and Solanum nigrum on HepG2 and CT26 cancer cell line
–Integrated Treatment of Aqueous Extract of Solanum nigrum-Potentiated Cisplatin- and Doxorubicin-Induced Cytotoxicity in Human Hepatocellular Carcinoma Cells
–Immunohistochemical, histopathological study and chemoprotective effect of Solanum nigrum in N-nitrosodiethylamine-induced hepatocellular carcinoma in Wistar rats
–Evaluation of uttroside B, a saponin from Solanum nigrum Linn, as a promising chemotherapeutic agent against hepatocellular carcinoma
–Solanum nigrum polysaccharide inhibits tumor growth in H22-bearing mice through regulation of caspase-3 and bcl-2.
–Induction of apoptosis in human hepatoma SMMC-7721 cells by solamargine from Solanum nigrum L.
–Solanum nigrum L. polyphenolic extract inhibits hepatocarcinoma cell growth by inducing G2/M phase arrest and apoptosis.
–Polyphenol-rich extracts from Solanum nigrum attenuated PKC alpha-mediated migration and invasion of hepatocellular carcinoma cells.
–Hydro-alcoholic extracts of Solanum Nigrii were cytotoxic against Liver Cancer cell lines, being more effective than extracts of Taxus baccata. (Shokrzadeh et al., Pharmacogn Mag, Jul 2010)
–A polyphenolic extract prepared from Solanum Nigrii was tested against HepG(2) Hepatocellular Cancer cells. The extract in doses of 1µ mL decreased tumor weight and volume by 90% in vivo and in vitro, inhibiting the cells in a dose-dependent manner. 2 µ mL doses caused an almost total elimination of tumor mass and tumor volume. (Wang et al., J Sci Food Agric, Jan 2011)
–Solamargine was isolated and purified from Solanum Nigrii, and tested against a number of cell lines. It showed significant inhibition of 6 cell lines, with strong inhibition of Liver Cancer (H22) and Ehrlich ascites tumor cell lines in doses of 2.4mg x kg dose i.v. (Tang et al., Zhongguo Zhong Yao Za Zhi, Aug 2011)
–Further, Solamargine was shown to induce apoptosis in human Hepatoma cells. (Ding et al., J Ethno-pharmacol, Jan 2012)

Tribulus, Ci Ji Li
–Aqueous extract of Tribulus terrestris Linn induces cell growth arrest and apoptosis by down-regulating NF-κB signaling in liver cancer cells.
–[Investigation on inhibitory and apoptosis-inducing effects of saponins from Tribulus terrestris on hepatoma cell line BEL-7402].
Withania
–Antioxidant activity and apoptotic induction as mechanisms of action of Withania somnifera (Ashwagandha) against a hepatocellular carcinoma cell line.

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