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Gastric Cancer
Gastric Cancer is a Cancer forming in the lining of the Stomach. It is the 5th most common cancer in the developed world and is the most common Gastrointestinal Cancer.
Initially there is often no symptoms. As the tumor progresses, Indigestion, Stomach discomfort and pain, bloating,. heartburn and nausea may appear. Feeling full after eating a small amount of food is also common.
Causes
Chronic Helicobacter pylori infection has been associated with greater increase of Gastric Cancer and is believed to be a contributing reason why China accounts for 40% of world Gastric Cancer cases.
Treatment
When found early, surgery to remove the Tumor is usually performed, along with Chemo- and Radiotherapy.
In advanced Gastric Cancer, the combination of Chinese Herbal Medicine in combination with Oxaliplatin had a 35% increase in effectiveness (see here).
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Western Tradition
Simples
Suggested Formulas
Decoction of Dodder of Thyme (Rhasis) Decoction for Cancer (Fuller) Decoction for Cancer (Model Botanic Guide to Health) Decoction Against Scrofula (Fuller) Syrup of Betony (Pharmacopoeia Augustana) Powder of Gum Lacca Greater (Dialacca Maj) (Mesue) Syrup of Fumitory Greater Syrup of Fumitory Compound (Augustana) Syrup of Dodder of Thyme (Mesue) Decoction of Dodder of Thyme (Mesue) Decoction of Dodder of Thyme (Rhasis) Indian Pills (Mesue) Pills for Melancholy (Unani) Arab Confect Purging Melancholy (Confectio Hamech) Selinum 6 (Tang kug drug thang) (Tibetan) |
Chinese Classification
Simples
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Special Formula
Stomach Cancer
Hedyotis Bai Hua She She Cao 2 oz.
Roots of Bulrush 1. oz.
Blackened ginger (Pao Jiang) 3 grams
Scutellaria barbata Ban Zhi Lian 15 grams
Gardenia Zhi Zi 9 grams
This is decocted. (Barefoot Doctors Manual)
Jian Pi Yang Wei Decoction
Astragalus Huang Qi
Codonopsis Dang Shen
Atractylodes Bai Zhu
Angelica Dang Gui
Paeonia Bai Shao
Citrus Chen Pi
Ginger processed Pinellia (Jiang Ban Xia)
Sparganium San Leng
Zedoary (E Zhu)
Salvia Dan Shen
Hedyotis Bai Hua She She Cao
Licorice
This formula was developed by an expert in Gastric Cancer treatment. In a study of 489 cases of Gastric Cancer followed up for 8 years, it was shown to reduce recurrence in stage II and III cancers by 32% compared to chemotherapy alone. It was also found to be synergistic with 5-Fu. (See Research here)
Cancer of the esophagus, stomach and colon:
Hedyotis Bai Hua She She Cao 60 grams
Dioscorea bulbifera Huang Yao Zi 60 grams
Sophora tonkinensis Shan Dou Gen 120 grams
Patrinia Bai Jiang Cao 120 grams
Dictamnus Bai Xian Pi 120 grams
Self Heal (Xia Ku Cao) 120 grams
Powder, mix with honey to make pills. Dose: 4 to 6 pills daily. (Chen & Chen)
Si Chong Formula
Earthworm (Di Long)
Scorpion (Quan Xie)
Centipede (Wu Gong)
Wingless Cockroach (Tu Bie Chong)
This has been studied.
Late-stage Gastric Cancer and Esophageal Cancer:
Toad Venom
Bezoar (artificial)
Lonicera Jin Yin Hua
Centipede (Wu Gong)
Dandelion (Pu Gong Ying)
Scutellaria barbata Ban Zhi Lian
Black Nightshade (Long Kui)
Pearl
Rhubarb (Da Huang)
Olibanum
Myrrh
Corydalis Yan Hu Suo
Safflower (Hong Hua)
Pinellia ginger-processed Ban Xia
Codonopsis Dang Shen
Astragalus Huang Qi
Amomum Sha Ren
(as in Jin Pu Jiao Nang of the Chinese Pharmacopoeia)
Side Effects of Chemotherapy
Ban Xia Xie Xin Decoction
Pinellia Ban Xia
Scutellaria Huang Qin
Ginseng
Coptis Huang Lian
Licorice
Ginger (Gan Jiang)
Jujube (Da Zao)
Attenuate chemotherapy-induced gastrointestinal toxicity and mucositis in Gastric and Colorectal Cancer patients. (See here)
Hedyotis Bai Hua She She Cao 2 oz.
Roots of Bulrush 1. oz.
Blackened ginger (Pao Jiang) 3 grams
Scutellaria barbata Ban Zhi Lian 15 grams
Gardenia Zhi Zi 9 grams
This is decocted. (Barefoot Doctors Manual)
Jian Pi Yang Wei Decoction
Astragalus Huang Qi
Codonopsis Dang Shen
Atractylodes Bai Zhu
Angelica Dang Gui
Paeonia Bai Shao
Citrus Chen Pi
Ginger processed Pinellia (Jiang Ban Xia)
Sparganium San Leng
Zedoary (E Zhu)
Salvia Dan Shen
Hedyotis Bai Hua She She Cao
Licorice
This formula was developed by an expert in Gastric Cancer treatment. In a study of 489 cases of Gastric Cancer followed up for 8 years, it was shown to reduce recurrence in stage II and III cancers by 32% compared to chemotherapy alone. It was also found to be synergistic with 5-Fu. (See Research here)
Cancer of the esophagus, stomach and colon:
Hedyotis Bai Hua She She Cao 60 grams
Dioscorea bulbifera Huang Yao Zi 60 grams
Sophora tonkinensis Shan Dou Gen 120 grams
Patrinia Bai Jiang Cao 120 grams
Dictamnus Bai Xian Pi 120 grams
Self Heal (Xia Ku Cao) 120 grams
Powder, mix with honey to make pills. Dose: 4 to 6 pills daily. (Chen & Chen)
Si Chong Formula
Earthworm (Di Long)
Scorpion (Quan Xie)
Centipede (Wu Gong)
Wingless Cockroach (Tu Bie Chong)
This has been studied.
Late-stage Gastric Cancer and Esophageal Cancer:
Toad Venom
Bezoar (artificial)
Lonicera Jin Yin Hua
Centipede (Wu Gong)
Dandelion (Pu Gong Ying)
Scutellaria barbata Ban Zhi Lian
Black Nightshade (Long Kui)
Pearl
Rhubarb (Da Huang)
Olibanum
Myrrh
Corydalis Yan Hu Suo
Safflower (Hong Hua)
Pinellia ginger-processed Ban Xia
Codonopsis Dang Shen
Astragalus Huang Qi
Amomum Sha Ren
(as in Jin Pu Jiao Nang of the Chinese Pharmacopoeia)
Side Effects of Chemotherapy
Ban Xia Xie Xin Decoction
Pinellia Ban Xia
Scutellaria Huang Qin
Ginseng
Coptis Huang Lian
Licorice
Ginger (Gan Jiang)
Jujube (Da Zao)
Attenuate chemotherapy-induced gastrointestinal toxicity and mucositis in Gastric and Colorectal Cancer patients. (See here)
Research
1. Multidrug Resistance of Gastric Cancer: The Mechanisms and Chinese Medicine Reversal Agents
2. The Potential Anticancer Activity of Phytoconstituents against Gastric Cancer—A Review on In Vitro, In Vivo, and Clinical Studies
3. Jianpi-yangwei decoction inhibits DNA damage repair in the drug resistance of gastric cancer by reducing FEN1 expression
Cannabis
–Cannabidiol promotes apoptosis via regulation of XIAP/Smac in gastric cancer
–Cannabidiol Induces Cell Cycle Arrest and Cell Apoptosis in Human Gastric Cancer SGC-7901 Cells
Crocus:
–Crocin triggers the apoptosis through increasing the Bax/Bcl-2 ratio and caspase activation in human gastric adenocarcinoma, AGS, cells.
–Anticancer effects of crocetin in both human adenocarcinoma gastric cancer cells and rat model of gastric cancer.
Peganum
-Anticancer activities of harmine by inducing a pro-death autophagy and apoptosis in human gastric cancer cells.
-Harmine induces apoptosis and inhibits tumor cell proliferation, migration and invasion through down-regulation of cyclooxygenase-2 expression in gastric cancer.
-[Harmine induces apoptosis in human SGC-7901 cells].
Rabdosia
–Oridonin Suppresses Human Gastric Cancer Growth in Vitro and in Vivo via Inhibition of VEGF, Integrin β3, and PCNA.
–Oridonin induces growth inhibition and apoptosis in human gastric carcinoma cells by enhancement of p53 expression and function.
–Oridonin induces apoptosis through the mitochondrial pathway in human gastric cancer SGC-7901 cells.
–Downregulation of Cdk1 and cyclinB1 expression contributes to oridonin-induced cell cycle arrest at G2/M phase and growth inhibition in SGC-7901 gastric cancer cells.
Solanum
–Purification, antitumor activity in vitro of steroidal glycoalkaloids from black nightshade (Solanum nigrum L.).
Withania
–Withaferin A inhibits the proliferation of gastric cancer cells by inducing G2/M cell cycle arrest and apoptosis.
2. The Potential Anticancer Activity of Phytoconstituents against Gastric Cancer—A Review on In Vitro, In Vivo, and Clinical Studies
3. Jianpi-yangwei decoction inhibits DNA damage repair in the drug resistance of gastric cancer by reducing FEN1 expression
Cannabis
–Cannabidiol promotes apoptosis via regulation of XIAP/Smac in gastric cancer
–Cannabidiol Induces Cell Cycle Arrest and Cell Apoptosis in Human Gastric Cancer SGC-7901 Cells
Crocus:
–Crocin triggers the apoptosis through increasing the Bax/Bcl-2 ratio and caspase activation in human gastric adenocarcinoma, AGS, cells.
–Anticancer effects of crocetin in both human adenocarcinoma gastric cancer cells and rat model of gastric cancer.
Peganum
-Anticancer activities of harmine by inducing a pro-death autophagy and apoptosis in human gastric cancer cells.
-Harmine induces apoptosis and inhibits tumor cell proliferation, migration and invasion through down-regulation of cyclooxygenase-2 expression in gastric cancer.
-[Harmine induces apoptosis in human SGC-7901 cells].
Rabdosia
–Oridonin Suppresses Human Gastric Cancer Growth in Vitro and in Vivo via Inhibition of VEGF, Integrin β3, and PCNA.
–Oridonin induces growth inhibition and apoptosis in human gastric carcinoma cells by enhancement of p53 expression and function.
–Oridonin induces apoptosis through the mitochondrial pathway in human gastric cancer SGC-7901 cells.
–Downregulation of Cdk1 and cyclinB1 expression contributes to oridonin-induced cell cycle arrest at G2/M phase and growth inhibition in SGC-7901 gastric cancer cells.
Solanum
–Purification, antitumor activity in vitro of steroidal glycoalkaloids from black nightshade (Solanum nigrum L.).
Withania
–Withaferin A inhibits the proliferation of gastric cancer cells by inducing G2/M cell cycle arrest and apoptosis.