Serenoa, Saw Palmetto
Sabal
Botanical name:
Serenoa repens (syn. S. serrulata, Chamaerops serrulata Sabal serrulata)
Parts used:
Ripe Fruit
Temperature & Taste:
Warm, Dry. Pungent, slightly Sweet
Classification:
Serenoa repens (syn. S. serrulata, Chamaerops serrulata Sabal serrulata)
Parts used:
Ripe Fruit
Temperature & Taste:
Warm, Dry. Pungent, slightly Sweet
Classification:
Uses:
1. Warms and Strengthens the Kidneys:
-Impotence
–urinary obstruction, Dysuria
-nocturnal urination
-Spermatorrhea
-Benign Prostatic Hypertrophy (BPH), Prostatitis
-it is also used for Prostate Cancer
-Ovarian pain or enlargement, Hypertrophy of the Uterus, Polycystic Ovarian Syndrome (PCOS)
-Infertility
-"We would rather regard it a remedy for prostatic irritation and relaxation of tissue than for a hypertrophied prostate". (King’s American Dispensatory, 1898)
2. Clears Cold Phlegm, Stops Cough:
-Cough, Whooping Cough,, Bronchitis
-Influenza
-Asthma, Wheezing
-Chronic Catarrh
3. Warms Stomach, Benefits Qi:
–promotes Digestion and assimilation
-increases strength and increase body weight when low
-Cachexia, Weakness, Convalesence
-"A good substitute for Cod Liver oil"
4. Externally:
–mixed with Cocoa butter and inserted into the vagina to strengthen, tone and firm up
Dose:
Dried Fruit in Decoction: 6–24 grams
Powder: 500mg–2 grams, twice daily
Fluid Extract: 1–60 drops
Dry Extract: 100–500mg twice daily
Dried Fruit in Decoction: 6–24 grams
Powder: 500mg–2 grams, twice daily
Fluid Extract: 1–60 drops
Dry Extract: 100–500mg twice daily
Main Combinations:
1. Prostatitis, BPH:
i. Saw Palmetto, Nettle root (this has been studied)
ii. Saw Palmetto, Avena, Willow (Salix nigra)
iii. Saw Palmetto, Sarsaparilla, Hydrangea
IV. Saw Palmetto, Saffron, Pinus massoniana (this has been studied)
2. Prostate Cancer:
i. Saw Palmetto, Rabdosia, Ganoderma Ling Zhi, Ginseng, Notoginseng (San Qi), Licorice
3. Dysuria:
i. Saw Palmetto, Nettle, Parsley seed
ii. Saw Palmetto, Tribulus
4. Cystitis, Saw Palmetto, Kava
5. To increase energy, Saw Palmetto, Ginseng, Kola, Damiana
6. Aphrodisiac:
i. Saw Palmetto, Ginseng,
ii. Saw Palmetto, Kola nut, Damiana
iii. Saw Palmetto, Kava, Cubeb
7. Spermatorrhea (coming from excess Mastrurbation or excess sex) Saw Palmetto, Avena
8. Heart weakness, Saw Palmetto, Hawthorn
9. Infertility:
i. Saw Palmetto, Kola nut, Damiana
ii. Saw Palmetto, Ginseng
10. To increase Breast size:
i. Saw Palmetto, Cumin seed, Fennel seed
ii. Saw Palmetto, Kola nut, Damiana
Major Formulas:
Cautions:
None noted
1. Occasional mild gastroinestinal symptoms may be seen.
2. There has been some speculation about the effect of Saw Palmetto on reducing male sex function. A meta-analysis failed to show any noticeable negative effect of male sexual function when compared to placebo.
Drug Interactions:
May interact with the Contraceptive Pill and other Hormone therapy.
Main Preparations used:
Extracts, especially Lipophilic Extracts are commonly used today for BPH.
None noted
1. Occasional mild gastroinestinal symptoms may be seen.
2. There has been some speculation about the effect of Saw Palmetto on reducing male sex function. A meta-analysis failed to show any noticeable negative effect of male sexual function when compared to placebo.
Drug Interactions:
May interact with the Contraceptive Pill and other Hormone therapy.
Main Preparations used:
Extracts, especially Lipophilic Extracts are commonly used today for BPH.
Click the Tabs above for more information on this Medicine
"Saw palmetto, Serenoa serrulata, Sabal serrulata. The berry of the saw palmetto, practically unknown in medicine before 1879, came rapidly into conspicuity, both in pharmacy and in medicine, after that date. It had been observed by the settlers of the South that animals feeding on the matured fruit "grew very sleek and fat," a fact that was ascribed to the therapeutic qualities of the berries, reasoning from which they prepared a decoction of the fruit for domestic medication. In 1877, Dr. Reed, of the Southern United States, in an article entitled "A New Remedy," in the Medical Brief, St. Louis, stated that several persons in his neighborhood were using a preparation of the berry, giving instances of its use in various directions. This article was reproduced in New Preparations, July, 1879, and was followed in the same publication by another article from the Medical Brief, in which Dr. I, J. M. Goss, then of Marietta, Georgia, states that he had been induced to use the remedy and considered it a satisfactory one. After this introduction the drug came repeatedly to the attention of practitioners of medicine. Manufacturing pharmacists gave it especial attention, and at the present time it is one of the most important remedial productions of the South. Thus the experimentation of the people, following its apparent effect on animals, was followed in turn by the investigations of the medical profession, and the remedy was finally introduced to the pages of the Pharmacopeia. In our opinion the volatile oil and its decomposition products are of exceeding interest and will yet be a prolific source of detailed research". (History of the vegetable drugs of the Pharmacopoeia of the United States, Lloyd, 1911)
PSA LEVELS:
–The effect of increasing doses of saw palmetto fruit extract on serum prostate specific antigen: analysis of the CAMUS randomized trial.
PROSTATITIS / BENIGN PROSTATIC HYPERPLASIA:
–Is Serenoa repens effective for the treatment of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)? A systematic review and meta-analysis.
–Serenoa repens for the Treatment of Lower Urinary Tract Symptoms Due to Benign Prostatic Enlargement: An Updated Cochrane Review.
–[PHYTOTHERAPY AND NATURAL AGENTS IN SYMPTOMATIC BENIGN PROSTATIC HYPERPLASIA (BPH)].
–Serenoa repens for the treatment of lower urinary tract symptoms due to benign prostatic enlargement.
–Lipidic extract of whole tomato reduces hyperplasia, oxidative stress and inflammation on testosterone-induced BPH in obese rats.
–The Role of Combination Therapy with alpha-Blockers and Hexanic Extract of Serenoa repens in the Treatment of LUTS/BPH.
–Permixon, hexane-extracted Serenoa repens, inhibits human prostate and bladder smooth muscle contraction and exerts growth-related functions in human prostate stromal cells.
–Hexanic Extract of Serenoa repens (Permixon()): A Review in Symptomatic Benign Prostatic Hyperplasia.
–Serenoa repens for the treatment of lower urinary tract symptoms due to benign prostatic enlargement: A systematic review and meta-analysis.
–The efficacy and safety of Serenoa repens extract for the treatment of patients with chronic prostatitis/chronic pelvic pain syndrome: a multicenter, randomized, double-blind, placebo-controlled trial.
–Dietary Factors and Supplements Influencing Prostate Specific-Antigen (PSA) Concentrations in Men with Prostate Cancer and Increased Cancer Risk: An Evidence Analysis Review Based on Randomized Controlled Trials.
–A double blind, placebo-controlled randomized comparative study on the efficacy of phytosterol-enriched and conventional saw palmetto oil in mitigating benign prostate hyperplasia and androgen deficiency.
–Comparison of Serenoa repens With Tamsulosin in the Treatment of Benign Prostatic Hyperplasia: A Systematic Review and Meta-Analysis.
–Use of saw palmetto (Serenoa repens) extract for benign prostatic hyperplasia.
–Efficacy and safety of a hexanic extract of Serenoa repens (Permixon() ) for the treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia (LUTS/BPH): systematic review and meta-analysis of randomised controlled trials and observational studies.
–Effects of Serenoa repens Alcohol Extract on Benign Prostate Hyperplasia.
RADIATION FOR PROSTATE CANCER:
–Saw Palmetto for Symptom Management During Radiation Therapy for Prostate Cancer.
COMBINED WITH NETTLE ROOT:
–Serenoa repens and Urtica dioica Fixed Combination: In-Vitro Validation of a Therapy for Benign Prostatic Hyperplasia (BPH).
–[A comparative analysis of the effectiveness of serenoa repens and serenoa repens in combination with urtica dioiccus for lower urinary symptoms suggestive of benign prostatic hyperplasia associated with chronic inflammation in prostate tissue].
EFFECT ON MALE SEX FUNCTION:
-Saw palmetto extract enhances erectile responses by inhibition of phosphodiesterase 5 activity and increase in inducible nitric oxide synthase messenger ribonucleic acid expression in rat and rabbit corpus cavernosum.
–Serenoa repens and its effects on male sexual function. A systematic review and meta-analysis of clinical trials.
EFFECT ON TESTOSTERONE AND SPERMATOGENESIS:
–Standardized Saw Palmetto Extract Directly and Indirectly Affects Testosterone Biosynthesis and Spermatogenesis.
–[Effect of saw palmetto extract on the reproductive function of male rats with chronic prostatitis].
POLYCYSTIC OVARIAN SYNDROME (PCOS)
–Polycystic Ovary Syndrome: A Disorder of Reproductive Age, Its Pathogenesis, and a Discussion on the Emerging Role of Herbal Remedies.
HAIR LOSS:
–Natural Compounds Used for Treating Hair Loss.
–Herbal preparations for the treatment of hair loss.
–An overview of herbal alternatives in androgenetic alopecia.
–Serenoa repens extracts promote hair regeneration and repair of hair loss mouse models by activating TGF-beta and mitochondrial signaling pathway.
–Treatment of male androgenetic alopecia with topical products containing Serenoa repens extract.
CANCER:
GLIOMA–Serenoa Repens Induces Growth Arrest, Apoptosis and Inactivation of STAT3 Signaling in Human Glioma Cells.
LIVER:
–New Natural Pigment Fraction Isolated from Saw Palmetto: Potential for Adjuvant Therapy of Hepatocellular Carcinoma.
PROSTATE:
–New chalcanonol glycoside from the seeds of saw palmetto: antiproliferative and antioxidant effects.
–Effect of Serenoa repens (Permixon) on the expression of inflammation-related genes: analysis in primary cell cultures of human prostate carcinoma.
–The effect of increasing doses of saw palmetto fruit extract on serum prostate specific antigen: analysis of the CAMUS randomized trial.
PROSTATITIS / BENIGN PROSTATIC HYPERPLASIA:
–Is Serenoa repens effective for the treatment of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS)? A systematic review and meta-analysis.
–Serenoa repens for the Treatment of Lower Urinary Tract Symptoms Due to Benign Prostatic Enlargement: An Updated Cochrane Review.
–[PHYTOTHERAPY AND NATURAL AGENTS IN SYMPTOMATIC BENIGN PROSTATIC HYPERPLASIA (BPH)].
–Serenoa repens for the treatment of lower urinary tract symptoms due to benign prostatic enlargement.
–Lipidic extract of whole tomato reduces hyperplasia, oxidative stress and inflammation on testosterone-induced BPH in obese rats.
–The Role of Combination Therapy with alpha-Blockers and Hexanic Extract of Serenoa repens in the Treatment of LUTS/BPH.
–Permixon, hexane-extracted Serenoa repens, inhibits human prostate and bladder smooth muscle contraction and exerts growth-related functions in human prostate stromal cells.
–Hexanic Extract of Serenoa repens (Permixon()): A Review in Symptomatic Benign Prostatic Hyperplasia.
–Serenoa repens for the treatment of lower urinary tract symptoms due to benign prostatic enlargement: A systematic review and meta-analysis.
–The efficacy and safety of Serenoa repens extract for the treatment of patients with chronic prostatitis/chronic pelvic pain syndrome: a multicenter, randomized, double-blind, placebo-controlled trial.
–Dietary Factors and Supplements Influencing Prostate Specific-Antigen (PSA) Concentrations in Men with Prostate Cancer and Increased Cancer Risk: An Evidence Analysis Review Based on Randomized Controlled Trials.
–A double blind, placebo-controlled randomized comparative study on the efficacy of phytosterol-enriched and conventional saw palmetto oil in mitigating benign prostate hyperplasia and androgen deficiency.
–Comparison of Serenoa repens With Tamsulosin in the Treatment of Benign Prostatic Hyperplasia: A Systematic Review and Meta-Analysis.
–Use of saw palmetto (Serenoa repens) extract for benign prostatic hyperplasia.
–Efficacy and safety of a hexanic extract of Serenoa repens (Permixon() ) for the treatment of lower urinary tract symptoms associated with benign prostatic hyperplasia (LUTS/BPH): systematic review and meta-analysis of randomised controlled trials and observational studies.
–Effects of Serenoa repens Alcohol Extract on Benign Prostate Hyperplasia.
RADIATION FOR PROSTATE CANCER:
–Saw Palmetto for Symptom Management During Radiation Therapy for Prostate Cancer.
COMBINED WITH NETTLE ROOT:
–Serenoa repens and Urtica dioica Fixed Combination: In-Vitro Validation of a Therapy for Benign Prostatic Hyperplasia (BPH).
–[A comparative analysis of the effectiveness of serenoa repens and serenoa repens in combination with urtica dioiccus for lower urinary symptoms suggestive of benign prostatic hyperplasia associated with chronic inflammation in prostate tissue].
EFFECT ON MALE SEX FUNCTION:
-Saw palmetto extract enhances erectile responses by inhibition of phosphodiesterase 5 activity and increase in inducible nitric oxide synthase messenger ribonucleic acid expression in rat and rabbit corpus cavernosum.
–Serenoa repens and its effects on male sexual function. A systematic review and meta-analysis of clinical trials.
EFFECT ON TESTOSTERONE AND SPERMATOGENESIS:
–Standardized Saw Palmetto Extract Directly and Indirectly Affects Testosterone Biosynthesis and Spermatogenesis.
–[Effect of saw palmetto extract on the reproductive function of male rats with chronic prostatitis].
POLYCYSTIC OVARIAN SYNDROME (PCOS)
–Polycystic Ovary Syndrome: A Disorder of Reproductive Age, Its Pathogenesis, and a Discussion on the Emerging Role of Herbal Remedies.
HAIR LOSS:
–Natural Compounds Used for Treating Hair Loss.
–Herbal preparations for the treatment of hair loss.
–An overview of herbal alternatives in androgenetic alopecia.
–Serenoa repens extracts promote hair regeneration and repair of hair loss mouse models by activating TGF-beta and mitochondrial signaling pathway.
–Treatment of male androgenetic alopecia with topical products containing Serenoa repens extract.
CANCER:
GLIOMA–Serenoa Repens Induces Growth Arrest, Apoptosis and Inactivation of STAT3 Signaling in Human Glioma Cells.
LIVER:
–New Natural Pigment Fraction Isolated from Saw Palmetto: Potential for Adjuvant Therapy of Hepatocellular Carcinoma.
PROSTATE:
–New chalcanonol glycoside from the seeds of saw palmetto: antiproliferative and antioxidant effects.
–Effect of Serenoa repens (Permixon) on the expression of inflammation-related genes: analysis in primary cell cultures of human prostate carcinoma.