Persica, Peach tree, Tao Ren 桃仁

Tao Ren (Peach kernel, TCM)
Klung kham  ཀླུང་ཁམ་ (Tibet)
Ortus Sanitatis, Meydenbach, 1491

Dioscorides Materia Medica, Mathias, 1563

Icones Plantarum Medcio-oeconomico, Vietz, 1806

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Botanical name:
Prunus persica

Parts used:
Kernels; Flowers; Leaf; Fruit

Temperature & Taste:
Kernel: Neutral in TCM (slightly Warm in the West); Moist. Bitter, Sweet
Leaf, Flower: Warm, dry.
Fruit: Cool, moist

Classifications:
2A APERIENT
3D. CORDIALS & CARDIACS.   3E. DIURETIC.    3F. LITHONTRIPTIC.    3G. EMMENAGOGUE.   3Q. ANTHELMINTIC
4e. STOMACHIC.    4h. NEPHRITIC

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Uses:
PEACH KERNEL:
1. Moves the Blood, Clears Stasis (TCM, West):
-menstrual disorders with fixed pain and dark or clotted Blood
-Tumors, Fibroids, Abdominal masses
-Lung and Intestinal abscess
-Trauma, Bruising

2. Promote Urine, Breaks Stones:
-Gravel and Stones (West)
-regarded as very useful for Stones, both to pass and relieve pain

3. Moves the Bowels (TCM, West):
-open Obstruction of the Liver: Jaundice
-used for abdominal pain
-gentle moist laxative laxative

4. Relieves Cough and Asthma:
-Cough, Wheezing and Asthma (used like Almond)

5. Kills Worms:
-commonly used in Europe to kill and expel Worms

6. Externally:
-externally used in Emulsions against Headaches
-kernels bruised and boiled in vinegar until it is thick, is applied to bald places to promote hair growth. (Culpeper)
-in Tibet to promote growth of hair (oil or decoction topically)


Dose:
KERNELS in DECOCTION: 3–6 grams

Substitute:
 ... available in PRO version

Main Combinations:
Peach kernel / Bitter Almond kernel & Saffron / Safflower

KERNEL:
1. Usually combined with Safflower (or Saffron) in TCM. Together, these activate the Blood and clear Blood Stasis.
2. Postpartum pain, Peach kernel with  ... available in PRO version
3. Apoplexy, Loss of Speech, prepare an emulsion of Peach kernels with  ... available in PRO version
4. To purge stagnant Blood, Peach kernel with  ... available in PRO version
5. Amenorrhea, Peach kernel with  ... available in PRO version
6. Leukorrhea, Peach kernels  ... available in PRO version
7. Jaundice, beat Peach kernels with  ... available in PRO version
8. Lung Cancer, Peach kernel,  ... available in PRO version
9. Dysuria, Peach kernel,  ... available in PRO version
10. Stones:
i. make an Electuary of Peach kernel with  ... available in PRO version
ii. take 18 or 20 Peach kernels with  ... available in PRO version
iii. Urinary stones  ... available in PRO version
11. Worms:
i. Peach kernels,  ... available in PRO version
ii. Peach kernels,  ... available in PRO version
iii. Peach kernels with  ... available in PRO version

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Cautions:
1. Not used during Pregnancy.
2. Avoid overdose of the kernel; overdose can be fatal.

Toxicity of the Kernel:
7-10 pieces can be fatal to children; 50–60 pieces for adults. This is due to hydrolysis of amygdalin which results in small amounts of hydrocyanic acid which inhibits the respiratory center. Symptoms of overdose include difficulty breathing, spasms, dilated pupils; serious cases may cause coma and death.

Drug Interactions
1. Hydrocyanic acid may potentiate the respiratory depressant effect of Morphine.

Main Preparations used:
Preserved Fruit, Water of the Flowers, Diuretic Water of the Kernels, Syrup of Peach Flowers, Conserve of Peach Flowers, Expressed Oil of Peach Kernels
  • Extra Info
  • Research
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GENERAL / REVIEW
–Toxicity and clinical reasonable application of Taoren (Semen Persi-cae) based on ancient and modern literature research

COMBINATIONS
–Taoren Honghua Drug Attenuates Atherosclerosis and Plays an Anti-Inflammatory Role in ApoE Knock-Out Mice and RAW264.7 Cells.
–Taoren-Honghua herb pair and its main components promoting blood circulation through influencing on hemorheology, plasma coagulation and platelet aggregation.
–Taoren-dahuang herb pair reduces eicosanoid metabolite shifts by regulating ADORA2A degradation activity in ischaemia/reperfusion injury rats.
–A multicenter, randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of Taoren Honghua Jian granule in patients with stable coronary artery disease.

ANTIBACTERIAL
–(leaf) Cytotoxic, antimicrobial and nitric oxide inhibitory activities of supercritical carbon dioxide extracted Prunus persica leaves.

ANTI-INFLAMMATORY
–Anti‑inflammatory role of Prunus persica L. Batsch methanol extract on lipopolysaccharide‑stimulated glial cells.

ANTIOXIDANT
–Multiple protective effect of peptides released from Olea europaea and Prunus persica seeds against oxidative damage and cancer cell proliferation.

ANTI-ALLERGY
–Anti-allergic inflammatory effects of cyanogenic and phenolic glycosides from the seed of Prunus persica.
–(fruit) Anti-allergic inflammatory activity of the fruit of Prunus persica: role of calcium and NF-kappaB.

PROMOTES CIRCULATION
–Taoren-Honghua herb pair and its main components promoting blood circulation through influencing on hemorheology, plasma coagulation and platelet aggregation.

SUBDURAL HEMATOMA
–Nonsurgical treatment of chronic subdural hematoma with Chinese herbal medicine: A STROBE-compliant retrospective study.

VASORELAXANT
–(branch) Endothelium-Dependent Vasorelaxant Effect of Prunus Persica Branch on Isolated Rat Thoracic Aorta.

ATHEROSCLEROSIS
–Taoren Honghua Drug Attenuates Atherosclerosis and Plays an Anti-Inflammatory Role in ApoE Knock-Out Mice and RAW264.7 Cells.

HEART DISEASE
–A multicenter, randomized, double-blind, placebo-controlled trial evaluating the efficacy and safety of Taoren Honghua Jian granule in patients with stable coronary artery disease.
HEPATOPROTECTIVE
–Phytochemical Screening and Protective Effects of Prunus persica Seeds Extract on Carbon Tetrachloride-Induced Hepatic Injury in Rats.
–The Effects of Taoren-Honghua Herb Pair on Pathological Microvessel and Angiogenesis-Associated Signaling Pathway in Mice Model of CCl4-Induced Chronic Liver Disease.

LIVER FIBROSIS
–Pharmacokinetics and anti-liver fibrosis characteristics of amygdalin: Key role of the deglycosylated metabolite prunasin.

NICOTINE TOXICITY
–(fruit) Protective Effect of White-fleshed Peach (Prunus persica (L.) Batsch) on Chronic Nicotine-induced Toxicity.

OBESITY (flowers)
–Anti-Obesity Effects of a Prunus persica and Nelumbo nucifera Mixture in Mice Fed a High-Fat Diet.
–Anti-Obesity Effects of the Flower of Prunus persica in High-Fat Diet-Induced Obese Mice.

CANCER
–Anti-tumor promoting effect of glycosides from Prunus persica seeds.
–Multiple protective effect of peptides released from Olea europaea and Prunus persica seeds against oxidative damage and cancer cell proliferation.
–Apoptosis induction of Persicae Semen extract in human promyelocytic leukemia (HL-60) cells.
-(leaf) Cytotoxic, antimicrobial and nitric oxide inhibitory activities of supercritical carbon dioxide extracted Prunus persica leaves.
–(root) Ethanol Extract of Root of Prunus persica Inhibited the Growth of Liver Cancer Cell HepG2 by Inducing Cell Cycle Arrest and Migration Suppression.
–(fruit) Polyphenolics from peach (Prunus persica var. Rich Lady) inhibit tumor growth and metastasis of MDA-MB-435 breast cancer cells in vivo.

SYNERGISTIC WITH CHEMOTHERAPY
–(fruit) Extract of Prunus persica flesh (PPFE) improves chemotherapeutic efficacy and protects against nephrotoxicity in cisplatin-treated mice.

PROTECTS AGAINST CHEMOTHERAPY TOXICITY
–(fruit) Extract of Prunus persica flesh (PPFE) improves chemotherapeutic efficacy and protects against nephrotoxicity in cisplatin-treated mice.
–(fruit) The pericarp extract of Prunus persica attenuates chemotherapy-induced acute nephrotoxicity and hepatotoxicity in mice.
–(fruit) The extract of Prunus persica flesh (PPFE) attenuates chemotherapy-induced hepatotoxicity in mice.

UV SKIN DAMAGE (flowers)
–The extract of the flowers of Prunus persica, a new cosmetic ingredient, protects against solar ultraviolet-induced skin damage in vivo.
–Protection against ultraviolet B- and C-induced DNA damage and skin carcinogenesis by the flowers of Prunus persica extract.
–Protection of the flowers of Prunus persica extract from ultraviolet B-induced damage of normal human keratinocytes.