Hepatica nobilis, Liverwort
Epatica, Lichen or Trefoil
Di Suo Luo (Marchantia polymorpha) (TCM)
Di Suo Luo (Marchantia polymorpha) (TCM)
Herbarius latinus, Petri, 1485
New Kreuterbuch, Matthiolus, 1563
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Krauterbuch, Lonitzer, 1578
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Botanical name:
There are over 9000 species of Liverwort, a number of species traditionally supplying the market:
Parts used:
Whole herb
Temperature & Taste:
Cool, dry. Slightly Bitter
Classifications:
2A APERIENT MEDICINES
4g. HEPATIC
There are over 9000 species of Liverwort, a number of species traditionally supplying the market:
- Marchantia polymorpha (Common Liverwort)
- Marchantia paleacea
- Conocephalum conicum (Greater Liverwort)
Parts used:
Whole herb
Temperature & Taste:
Cool, dry. Slightly Bitter
Classifications:
2A APERIENT MEDICINES
4g. HEPATIC
Uses:
1. Clears Damp-Heat, Benefits the Liver, Opens Obstructions:
-cleanses the Blood
-obstructions of the Liver and Spleen
-Jaundice
-Damp-Heat Edema, Strangury, Dysuria
-'good for Liver heat, and for Jaundice' (Herbarius latinus, Petri, 1485)
-'a singular good herb for all diseases of the Liver' (Culpeper)
2. Clears Heat, Resists Toxin, Promotes Healing:
-Fever, Tertian Fever
-Wounds (West, TCM)
-Toxic Sores and Abscesses (West, TCM)
-Snake Bite (TCM)
-also used for Rabies (West)
-hemoptysis, hematuria, and internal ulcers
-recently shown to be useful for Cancer
-'Inflammations in any part'; (Culpeper)
3. Benefits Lungs, Stops Cough:
-Chronic Lung disease
-Pleurisy, Tuberculosis
4. Benefits the Womb
-cleanses Afterbirth
-Menopause
-Leukorrhea, Spermatorrhea
5. Externally:
-Wounds, Fractures, Ulcers
-skin inflammation, redness, Rashes
-Tonsillitis
-Burns and Scalds (TCM)
-Cures Ruptures (Hernia)
Dose:
Infusion: 1 spoonful per cup
Decoction: 3–9 grams
Powder: 1–4 grams
Infusion: 1 spoonful per cup
Decoction: 3–9 grams
Powder: 1–4 grams
Main Combinations:
1. Liver Heat:
i. Liverwort decocted with Endive (Herbarius latinus, Petri, 1485)
ii. Liverwort with Centaury and Dandelion
iii. Liverwort, Endive, Lettuce, Violet, Raisins, Prunes, decocted together and form a syrup. (Herbarius latinus, Petri, 1485)
iv. Liverwort with Barley, Asparagus root, Chicory, Dandelion, Fumitory, Hops, Licorice, Dodder (as in Syrup of Chicory and Rhubarb of Nicholas)
2. Inflammation of the Liver, Liverwort with Scarlet Pimpernel, Walnut leaf, Juniper berry, Heartsease, Alder Buckthorn (Frangula) bark (Ulrich)
3. Obstruction of the Liver with Heat:
i. Liverwort, Endive, 4 Cold Seeds, Chicory, Sorrel, Maidenhair, Cyperus rotundus (Wirtzung)
ii. Liverwort, Senna, Fumitory, Maidenhair, Dodder, Licorice (Fioravanti, 1659)
4. Obstruction of ther Spleen or Liver from Heat, Liverwort, Hart's Tongue (Scolopendrum), Endive, decocted
5. Jaundice, Liverwort, Ivory, Saffron
6. Edema, Liverwort, Horehound, Wormwood, Sorrel (Pharmacopœia Bateana)
7. Cough, Consumption, Liverwort, Lungwort, Hyssop, Violet, Strawberry leaf, Licorice, Aniseed (Fioravanti, 1659)
8. Rabies, Liverwort (2 parts), Pepper (1 part), taken in 1 ½ dram doses.
9. Burning Fever, Liverwort, Endive, Plantain, Purslane, Violet (Wirtzung)
10. Pleurisy from Heat, Liverwort, Endive, White Dittany, Maidenhair (1 handful each), 4 Cold seeds (half oz.), Barley, Licorice, Jujubes (1 dram each), Violet, Water Lilly (half oz.) (Wirtzung)
Major Formulas:
Syrup of Chicory and Rhubarb (Nicholas)
Green Ointment:
Fresh Juniper berries (3 oz.), Fresh herbs of Southernwood, Mugwort, Easter Daisy, Betony, Fennel, Hyssop, Mint, Liverwort, Yarrow, Marjoram, Plantain, Veronica, Vervain, Sage, Rue (of each 1 oz.), Butter (48 oz.). Boil until the herbs crisp, and strain
Cautions:
None noted
Main Preparations used:
None noted
Main Preparations used:
Click the Tabs above for more information on this Medicine
GENERAL / REVIEW
–Pharmacological potential of genus Marchantia: A Review
ANTIBACTERIAL
–Isolation and antibacterial activity of marchantin A, a cyclic bis(bibenzyl) constituent of Hungarian Marchantia polymorpha.
–Antimicrobial Activity of Extracts of Marchantia polymorpha
–Five phenolic compounds from Marchantia polymorpha L. and their in vitro antibacterial, antioxidant and cytotoxic activities
ANTI-FUNGAL
–Antifungal bis[bibenzyls] from the Chinese liverwort Marchantia polymorpha L.
–Evaluation of antifungal potential of Marchantia polymorpha L., Dryopteris filix-mas (L.) Schott and Ephedra foliata Boiss. against phyto fungal pathogens
ANTI-VIRAL / COVID
–SARS-CoV-2 Fears Green: The Chlorophyll Catabolite Pheophorbide A Is a Potent Antiviral.
ANTI-INFLAMMATORY
–Anti-Inflammatory Effect of Liverwort (Marchantia polymorpha L.) and Racomitrium Moss (Racomitrium canescens (Hedw.) Brid.) Growing in Korea.
–In vitro anti-inflammatory and antioxidant activity of ethanolic extract of Marchantia polymorpha in Kumaun region
ANTIOXIDANT
–Marchantia polymorpha L. Flavonoids Protect Liver From CCl4-Induced Injury by Antioxidant and Gene-Regulatory Effects.
–In vitro anti-inflammatory and antioxidant activity of ethanolic extract of Marchantia polymorpha in Kumaun region
–Five phenolic compounds from Marchantia polymorpha L. and their in vitro antibacterial, antioxidant and cytotoxic activities
HEPATOPROTECTIVE
–Marchantia polymorpha L. Flavonoids Protect Liver From CCl4-Induced Injury by Antioxidant and Gene-Regulatory Effects.
ACETYLCHOLESTERASE INHIBITION
–Flavonoids, Antioxidant Potential, and Acetylcholinesterase Inhibition Activity of the Extracts from the Gametophyte and Archegoniophore of Marchantia polymorpha
CANCER
–Phytochemical Profile and Anticancer Potential of Endophytic Microorganisms from Liverwort Species, Marchantia polymorpha L.
–Cytotoxicity of Marchantia convoluta leaf extracts to human liver and lung cancer cells
BREAST
–Synergistic cytotoxic effect of the microtubule inhibitor marchantin A from Marchantia polymorpha and the Aurora kinase inhibitor MLN8237 on breast cancer cells in vitro.
–Five phenolic compounds from Marchantia polymorpha L. and their in vitro antibacterial, antioxidant and cytotoxic activities
LIVER
–Marchantia polymorpha L. ethanol extract induces apoptosis in hepatocellular carcinoma cells via intrinsic- and endoplasmic reticulum stress-associated pathways.
–Pharmacological potential of genus Marchantia: A Review
ANTIBACTERIAL
–Isolation and antibacterial activity of marchantin A, a cyclic bis(bibenzyl) constituent of Hungarian Marchantia polymorpha.
–Antimicrobial Activity of Extracts of Marchantia polymorpha
–Five phenolic compounds from Marchantia polymorpha L. and their in vitro antibacterial, antioxidant and cytotoxic activities
ANTI-FUNGAL
–Antifungal bis[bibenzyls] from the Chinese liverwort Marchantia polymorpha L.
–Evaluation of antifungal potential of Marchantia polymorpha L., Dryopteris filix-mas (L.) Schott and Ephedra foliata Boiss. against phyto fungal pathogens
ANTI-VIRAL / COVID
–SARS-CoV-2 Fears Green: The Chlorophyll Catabolite Pheophorbide A Is a Potent Antiviral.
ANTI-INFLAMMATORY
–Anti-Inflammatory Effect of Liverwort (Marchantia polymorpha L.) and Racomitrium Moss (Racomitrium canescens (Hedw.) Brid.) Growing in Korea.
–In vitro anti-inflammatory and antioxidant activity of ethanolic extract of Marchantia polymorpha in Kumaun region
ANTIOXIDANT
–Marchantia polymorpha L. Flavonoids Protect Liver From CCl4-Induced Injury by Antioxidant and Gene-Regulatory Effects.
–In vitro anti-inflammatory and antioxidant activity of ethanolic extract of Marchantia polymorpha in Kumaun region
–Five phenolic compounds from Marchantia polymorpha L. and their in vitro antibacterial, antioxidant and cytotoxic activities
HEPATOPROTECTIVE
–Marchantia polymorpha L. Flavonoids Protect Liver From CCl4-Induced Injury by Antioxidant and Gene-Regulatory Effects.
ACETYLCHOLESTERASE INHIBITION
–Flavonoids, Antioxidant Potential, and Acetylcholinesterase Inhibition Activity of the Extracts from the Gametophyte and Archegoniophore of Marchantia polymorpha
CANCER
–Phytochemical Profile and Anticancer Potential of Endophytic Microorganisms from Liverwort Species, Marchantia polymorpha L.
–Cytotoxicity of Marchantia convoluta leaf extracts to human liver and lung cancer cells
BREAST
–Synergistic cytotoxic effect of the microtubule inhibitor marchantin A from Marchantia polymorpha and the Aurora kinase inhibitor MLN8237 on breast cancer cells in vitro.
–Five phenolic compounds from Marchantia polymorpha L. and their in vitro antibacterial, antioxidant and cytotoxic activities
LIVER
–Marchantia polymorpha L. ethanol extract induces apoptosis in hepatocellular carcinoma cells via intrinsic- and endoplasmic reticulum stress-associated pathways.