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Bacopa, Brahmi
Water Hyssop, Indian Pennywort
Brahmi (Ayurveda)
Pirammi Vazukkai (Siddha)
Brahmi (Unani)
Brahmi (Ayurveda)
Pirammi Vazukkai (Siddha)
Brahmi (Unani)
M. Blanco, Flora de Filipinas. (1875)
Botanical name:
Bacopa spp.:
Parts used:
Whole plant
Temperature & Taste:
Neutral/slightly Warm. Bitter.
Bacopa spp.:
- B. monnieri (syn. B. monniera, Herpestis monniera, Moniera cuneifolia)
- B. floribunda
Parts used:
Whole plant
Temperature & Taste:
Neutral/slightly Warm. Bitter.
Uses:
1. Settles Wind, Calms the Mind:
-Neurasthenia, Nervous Breakdown
-Anxiety, Anxiety neurosis
-Convulsions, Epilepsy, Hysteria
-Insanity, Mental Illness
-Addiction and Withdrawal
-also for Hypertension and Angina
-the extract was also found to be a potent analgesic
2. Benefits Brain
-enhances learning and memory (proven effect)
-Senile Dementia, Alzheimer's
-improves intellect (proven effect)
-beneficial for those doing lots of mental work or study
-Headache due to mental exhaustion
-also reputedly effective for Hydrocephalus
3. Clears Heat and Toxin:
-Fever; Malarial Fever
-Hoarseness, Bronchitis
-Hepato-protective
-Snake Bite
4. Benefits Stomach:
-Indigestion (especially related to stress)
-recently used for Irritable Bowel Syndrome with success
5. Benefits the Uterus:
-Infertility
-threatened Miscarriage (Charaka)
6. Externally:
-Skin diseases
-Ulcers
Dose:
1. Fresh leaf or Juice are often preferred.
Of the Juice: 10–30 mls, twice daily (usually with Honey), before breakfast and bed to benefit the brain, enhance learning and memory.
Juice with Milk was prescribed as an anti-ageing tonic and to promote intellect. (Sushruta)
Powder of the Whole Plant: 3–5 grams
Root Powder: 500mg–1.5 grams
Comment:
1. The literal meaning of Brahmi is 'expand consciousness'.
2. The primary alkaloid Brahmine has similar stimulating effects to strychnine, but is far less toxic.
Substitute:
Centella asciatica is also known as Brahmi and is used as a substitute.
1. Fresh leaf or Juice are often preferred.
Of the Juice: 10–30 mls, twice daily (usually with Honey), before breakfast and bed to benefit the brain, enhance learning and memory.
Juice with Milk was prescribed as an anti-ageing tonic and to promote intellect. (Sushruta)
Powder of the Whole Plant: 3–5 grams
Root Powder: 500mg–1.5 grams
Comment:
1. The literal meaning of Brahmi is 'expand consciousness'.
2. The primary alkaloid Brahmine has similar stimulating effects to strychnine, but is far less toxic.
Substitute:
Centella asciatica is also known as Brahmi and is used as a substitute.
Main Combinations:
1. To enhance Mental function, Memory and Learning:
i. whole plant of Bacopa is heated in Ghee, strained, and a teaspoon taken every morning
ii. Bacopa with Calamus
iii. Bacopa with Centella
iv. Bacopa with Ginkgo leaf
v. Bacopa with Walnut
vi. Bacopa with Convolvulus Shankhapushpi
vii. Bacopa with Convolvulus Shankhapushpi, Euphorbia dracunculoides
viii. Bacopa with Withania and Calamus
ix. Bacopa, Centella, Oroxylum, Withania, Chebula, Indian Spikenard
x. Bacopa, Ginseng, Calamus
xi. Bacopa, Ginseng, Eleutherococcus
xii. Bacopa, Withania, Centella, Indian Spikenard, Almond, Triphala
xiii. Centella, Bacopa, Withania, Chebula, Indian Spikenard
xiv. Bacopa, Withania, Almond, Date, Black Pepper made into an Electuary with Honey (Unani)
2. To benefits Students and those doing lots of mental work:
i. Bacopa and Withania
ii. Bacopa with Centella, Convolvulus Shankhapushpi
iii. Bacopa with Calamus, Withania and Honey
iv. Bacopa with Balm, Rosemary, Calamus
3. Retarded or delayed development:
i. Bacopa, Withania, Calamus, Almond
ii. Bacopa, Ginseng, Walnut
4. Insanity, Psychosis:
i. Bacopa with Calamus
ii. Bacopa with Convolvulus Shankhapushpi
iii. Bacopa, Alstonia, Withania
iv. Bacopa with Withania, Calamus, Convolvulus Shankhapushpi
v. Bacopa with Rauwolfia
vi. Bacopa, Calamus, Costus, Convolvulus Shankhapushpi in aged Ghee (Charaka)
vii. Bacopa, Centella, Indian Spikenard, Mucuna, Calamus in Ghee (Charaka)
viii. equal parts of the fresh juice of Bacopa, Benincasa and Tenolepsis, mixed with Costus powder and Honey.
5. Epilepsy, Insanity, Infertility, Mental Retardation, Bacopa with Ginger, Long Pepper, Convolvulus Shankhpushpi, Turpeth, Embelia, Cassia Fistula (as in Brahmi Ghirta)
6. Alzheimer's Disease:
i. Bacopa with Ginkgo leaf, Rosemary
ii. Bacopa, Dioscorea bulbifera, Sea Buckthorn
7. Parkinson's Disease, Bacopa, Withania, Mucuna
8. Anxiety, Nervousness:
i. Bacopa, Valerian, St. Johns wort
ii. Bacopa, Centella, Chrysanthemum indicum (Ye Ju Hua), Convolvulus Shanhapushpi
9. Depression, Bacopa with St. Johns wort, Balm, Withania
10. Addiction or Withdrawal, Bacopa with California Poppy, Scullcap
11. Convulsions and Nervous Debility:
i. Bacopa, Calamus, Alpinia speciosa
ii. Bacopa, Mucuna, Centella, Indian Spikenard, Valerian, Tribulus
12. Irritable Bowel Syndrome, Bacopa with Aegle (trials demonstrated improvement in 65% of patients)
13. Hoarseness, Bacopa, Adhatoda, Calamus, Chebula, Long Pepper with Honey
14. Heat-Toxin skin diseases:
i. Bacopa, Neem
ii. Bacopa, Violet, Fumitory
15. Cataract, Bacopa, Asparagus root, Boerhaavia
Major Formulas:
Brahmi Ghirta
Cautions:
High doses aggravate Pitta (Bile)
Toxicity:
–Acute and chronic toxicities of Bacopa monnieri extract in Sprague-Dawley rats.
Drug Interaction:
1. May interact with anti-seizure, antipsychotic, and antidepressant medication
2. Suspected cholinergic toxicity due to cevimeline hydrochloride and Bacopa monnieri interaction: a case report.
Main Preparations used:
High doses aggravate Pitta (Bile)
Toxicity:
–Acute and chronic toxicities of Bacopa monnieri extract in Sprague-Dawley rats.
Drug Interaction:
1. May interact with anti-seizure, antipsychotic, and antidepressant medication
2. Suspected cholinergic toxicity due to cevimeline hydrochloride and Bacopa monnieri interaction: a case report.
Main Preparations used:
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GENERAL /REVIEW:
–Pharmacological attributes of Bacopa monnieri extract: Current updates and clinical manifestation.
–Bacopa monnieri
–Neuropharmacological review of the nootropic herb Bacopa monnieri.
–Bacosides from Bacopa monnieri extract: An overview of the effects on neurological disorders.
–Neuropharmacological and cognitive effects of Bacopa monnieri (L.) Wettst - A review on its mechanistic aspects.
–In Vitro Propagation, Phytochemical and Neuropharmacological Profiles of Bacopa monnieri (L.) Wettst.: A Review.
–A comparative pharmacognostical and preliminary physico-chemical analysis of stem and leaf of Bacopa monnieri (L.) Pennel and Bacopa floribunda (R.BR.) Wettst.
EFFECT OF DRYING:
–Effect of different drying treatments on the physicochemical, functional, and antioxidant properties of Bacopa monnieri.
ANTIBACTERIAL:
–Antibacterial Potential of Bacopa monnieri (L.) Wettst. and Its Bioactive Molecules against Uropathogens-An In Silico Study to Identify Potential Lead Molecule(s) for the Development of New Drugs to Treat Urinary Tract Infections.
–Phytotoxic and antimicrobial constituents of Bacopa monnieri and Holmskioldia sanguinea.
ANTIOXIDANT:
–Phenyl glycosides from Bacopa monnieri with their antioxidant and anti-inflammatory activities.
ANTI-INFLAMMATORY:
–Phenyl glycosides from Bacopa monnieri with their antioxidant and anti-inflammatory activities.
–The Ayurvedic plant Bacopa monnieri inhibits inflammatory pathways in the brain.
–Bacopa monnieri (L.) exerts anti-inflammatory effects on cells of the innate immune system in vitro.
INHIBITS CYTOCHROME P450:
–Inhibition of human cytochrome P450 enzymes by Bacopa monnieri standardized extract and constituents.
HYPOTENTIVE:
–Bacopa monnieri and its constituents is hypotensive in anaesthetized rats and vasodilator in various artery types.
VASODILATORY:
–Bacopa monnieri and its constituents is hypotensive in anaesthetized rats and vasodilator in various artery types.
BRAIN / CNS DISORDERS:
–Bacopa monnieri for Disorders Affecting Brain: Current Perspectives.
–Traditional Herbal Medicines Against CNS Disorders from Bangladesh.
NEUROPROTECTIVE:
–Neuroprotection with Bacopa monnieri-A review of experimental evidence.
–Neuroprotective effect of the standardised extract of Bacopa monnieri (BacoMind) in valproic acid model of autism spectrum disorder in rats.
–Neuroprotective Potential of Bacopa monnieri: Modulation of Inflammatory Signals.
–A Comprehensive Review on Preclinical Evidence-based Neuroprotective Potential of Bacopa monnieri against Parkinson's Disease.
–Investigating neuroprotective roles of Bacopa monnieri extracts: Mechanistic insights and therapeutic implications.
–Cognitive enhancement and neuroprotective effects of Bacopa monnieri in Alzheimer's disease model.
–Neuroprotective role of Bacopa monnieri extract in modulating depression in an experimental rat model.
–Improved neuroprotective effects by combining Bacopa monnieri and Rosmarinus officinalis supercritical CO2 extracts.
–Bacopa Protects against Neurotoxicity Induced by MPP+ and Methamphetamine.
ANXIETY & DEPRESSION:
–Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial.
SCHIZOPHRENIA:
–Bio-Computational Evaluation of Compounds of Bacopa Monnieri as a Potential Treatment for Schizophrenia.
–Bacopa monnieri (Brahmi) improved novel object recognition task and increased cerebral vesicular glutamate transporter type 3 in sub-chronic phencyclidine rat model of schizophrenia.
EPILEPSY:
–Bacopa monnieri and Bacoside-A for ameliorating epilepsy associated behavioral deficits.
COGNITIVE EFFECTS:
–Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract.
–Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial.
–The cognitive-enhancing effects of Bacopa monnieri: a systematic review of randomized, controlled human clinical trials.
–Neuropharmacological and cognitive effects of Bacopa monnieri (L.) Wettst - A review on its mechanistic aspects.
–Bacopa monnieri (L.) Ameliorates Cognitive Deficits Caused in a Trimethyltin-Induced Neurotoxicity Model Mice.
–Cognitive enhancement and neuroprotective effects of Bacopa monnieri in Alzheimer's disease model.
–The Neurocognitive Effects of Bacopa monnieri and Cognitive Training on Markers of Brain Microstructure in Healthy Older Adults.
–Protective effects of Bacopa monnieri on ischemia-induced cognitive deficits in mice: the possible contribution of bacopaside I and underlying mechanism.
–Mechanisms, Efficacy, and Safety of Bacopa monnieri (Brahmi) for Cognitive and Brain Enhancement.
MEMORY:
–Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial.
–Bacopa monnieri ameliorates memory deficits in olfactory bulbectomized mice: possible involvement of glutamatergic and cholinergic systems.
–Chronic effects of Brahmi (Bacopa monnieri) on human memory.
ALZHEIMER'S DISEASE / DEMENTIA:
–Brahmi (Bacopa monnieri): An ayurvedic herb against the Alzheimer's disease.
–Use of Bacopa monnieri in the Treatment of Dementia Due to Alzheimer Disease: Systematic Review of Randomized Controlled Trials.
–Bacopa monnieri, a Neuroprotective Lead in Alzheimer Disease: A Review on Its Properties, Mechanisms of Action, and Preclinical and Clinical Studies.
–Bacopa monnieri as an Antioxidant Therapy to Reduce Oxidative Stress in the Aging Brain.
–Neurocognitive Effect of Nootropic Drug Brahmi (Bacopa monnieri) in Alzheimer's Disease.
–Bacopa monnieri prevents colchicine-induced dementia by anti-inflammatory action.
–Synergistic neuroprotection by phytocompounds of Bacopa monnieri in scopolamine-induced Alzheimer's disease mice model.
–Cognitive enhancement and neuroprotective effects of Bacopa monnieri in Alzheimer's disease model.
–Efficacy of Bacopa Monnieri (Brahmi) and Donepezil in Alzheimer's Disease and Mild Cognitive Impairment: A Randomized Double-Blind Parallel Phase 2b Study.
–Amelioration of Amyloid-β Induced Alzheimer's Disease by Bacopa monnieri through Modulation of Mitochondrial Dysfunction and GSK-3β/Wnt/β-Catenin Signaling.
–A Computational Study of Natural Compounds from Bacopa monnieri in the Treatment of Alzheimer's Disease.
–Neuroprotective effects of Bacopa monnieri in experimental model of dementia.
PARKINSON'S DISEASE:
–Bacopa monnieri in Patients with Parkinson's Disease: A Pilot Study.
–A Comprehensive Review on Preclinical Evidence-based Neuroprotective Potential of Bacopa monnieri against Parkinson's Disease.
–Neuroprotective effects of Bacopa monnieri in Parkinson's disease model.
–Anti-Parkinsonian effects of Bacopa monnieri: insights from transgenic and pharmacological Caenorhabditis elegans models of Parkinson's disease.
–Neuroprotective and Neurorescue Mode of Action of Bacopa monnieri (L.) Wettst in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Parkinson's Disease: An In Silico and In Vivo Study.
DIABETES:
–Antihyperglycemic activity of bacosine, a triterpene from Bacopa monnieri, in alloxan-induced diabetic rats.
OPIOID TOXICITY:
–Beneficial effects of Bacopa monnieri extract on opioid induced toxicity.
–Neuroprotective effect of Bacopa monnieri against morphine-induced histopathological changes in the cerebellum of rats.
METHAMPHETAMINE TOXICITY:
–Bacopa Protects against Neurotoxicity Induced by MPP+ and Methamphetamine.
ULCERATIVE COLITIS:
–Exploring the ameliorative potential of Bacopa monnieri in acetic acid induced ulcerative colitis in mice.
RENOPROTECTIVE:
–Renoprotective effect of Bacopa monnieri via inhibition of advanced glycation end products and oxidative stress in STZ-nicotinamide-induced diabetic nephropathy.
CANCER:
–The Evolving Roles of Bacopa monnieri as Potential Anti-Cancer Agent: A Review.
–Advanced network pharmacology study reveals multi-pathway and multi-gene regulatory molecular mechanism of Bacopa monnieri in liver cancer based on data mining, molecular modeling, and microarray data analysis.
–Anticancer activity of Bacopa monnieri through apoptosis induction and mitophagy-dependent NLRP3 inflammasome inhibition in oral squamous cell carcinoma.
–Evaluation of anticancer potential of Bacopa monnieri L. against MCF-7 and MDA-MB 231 cell line.
–Chemopreventive and Anticancer Activities of Bacopa monnieri Extracted from Artificial Digestive Juices.
–The Purified Extract from the Medicinal Plant Bacopa monnieri, Bacopaside II, Inhibits Growth of Colon Cancer Cells In Vitro by Inducing Cell Cycle Arrest and Apoptosis.
–Cytotoxic and anti -tumour properties of ethanolic extract of bacopa monnieri (L) penn.
–Pharmacological attributes of Bacopa monnieri extract: Current updates and clinical manifestation.
–Bacopa monnieri
–Neuropharmacological review of the nootropic herb Bacopa monnieri.
–Bacosides from Bacopa monnieri extract: An overview of the effects on neurological disorders.
–Neuropharmacological and cognitive effects of Bacopa monnieri (L.) Wettst - A review on its mechanistic aspects.
–In Vitro Propagation, Phytochemical and Neuropharmacological Profiles of Bacopa monnieri (L.) Wettst.: A Review.
–A comparative pharmacognostical and preliminary physico-chemical analysis of stem and leaf of Bacopa monnieri (L.) Pennel and Bacopa floribunda (R.BR.) Wettst.
EFFECT OF DRYING:
–Effect of different drying treatments on the physicochemical, functional, and antioxidant properties of Bacopa monnieri.
ANTIBACTERIAL:
–Antibacterial Potential of Bacopa monnieri (L.) Wettst. and Its Bioactive Molecules against Uropathogens-An In Silico Study to Identify Potential Lead Molecule(s) for the Development of New Drugs to Treat Urinary Tract Infections.
–Phytotoxic and antimicrobial constituents of Bacopa monnieri and Holmskioldia sanguinea.
ANTIOXIDANT:
–Phenyl glycosides from Bacopa monnieri with their antioxidant and anti-inflammatory activities.
ANTI-INFLAMMATORY:
–Phenyl glycosides from Bacopa monnieri with their antioxidant and anti-inflammatory activities.
–The Ayurvedic plant Bacopa monnieri inhibits inflammatory pathways in the brain.
–Bacopa monnieri (L.) exerts anti-inflammatory effects on cells of the innate immune system in vitro.
INHIBITS CYTOCHROME P450:
–Inhibition of human cytochrome P450 enzymes by Bacopa monnieri standardized extract and constituents.
HYPOTENTIVE:
–Bacopa monnieri and its constituents is hypotensive in anaesthetized rats and vasodilator in various artery types.
VASODILATORY:
–Bacopa monnieri and its constituents is hypotensive in anaesthetized rats and vasodilator in various artery types.
BRAIN / CNS DISORDERS:
–Bacopa monnieri for Disorders Affecting Brain: Current Perspectives.
–Traditional Herbal Medicines Against CNS Disorders from Bangladesh.
NEUROPROTECTIVE:
–Neuroprotection with Bacopa monnieri-A review of experimental evidence.
–Neuroprotective effect of the standardised extract of Bacopa monnieri (BacoMind) in valproic acid model of autism spectrum disorder in rats.
–Neuroprotective Potential of Bacopa monnieri: Modulation of Inflammatory Signals.
–A Comprehensive Review on Preclinical Evidence-based Neuroprotective Potential of Bacopa monnieri against Parkinson's Disease.
–Investigating neuroprotective roles of Bacopa monnieri extracts: Mechanistic insights and therapeutic implications.
–Cognitive enhancement and neuroprotective effects of Bacopa monnieri in Alzheimer's disease model.
–Neuroprotective role of Bacopa monnieri extract in modulating depression in an experimental rat model.
–Improved neuroprotective effects by combining Bacopa monnieri and Rosmarinus officinalis supercritical CO2 extracts.
–Bacopa Protects against Neurotoxicity Induced by MPP+ and Methamphetamine.
ANXIETY & DEPRESSION:
–Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial.
SCHIZOPHRENIA:
–Bio-Computational Evaluation of Compounds of Bacopa Monnieri as a Potential Treatment for Schizophrenia.
–Bacopa monnieri (Brahmi) improved novel object recognition task and increased cerebral vesicular glutamate transporter type 3 in sub-chronic phencyclidine rat model of schizophrenia.
EPILEPSY:
–Bacopa monnieri and Bacoside-A for ameliorating epilepsy associated behavioral deficits.
COGNITIVE EFFECTS:
–Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract.
–Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial.
–The cognitive-enhancing effects of Bacopa monnieri: a systematic review of randomized, controlled human clinical trials.
–Neuropharmacological and cognitive effects of Bacopa monnieri (L.) Wettst - A review on its mechanistic aspects.
–Bacopa monnieri (L.) Ameliorates Cognitive Deficits Caused in a Trimethyltin-Induced Neurotoxicity Model Mice.
–Cognitive enhancement and neuroprotective effects of Bacopa monnieri in Alzheimer's disease model.
–The Neurocognitive Effects of Bacopa monnieri and Cognitive Training on Markers of Brain Microstructure in Healthy Older Adults.
–Protective effects of Bacopa monnieri on ischemia-induced cognitive deficits in mice: the possible contribution of bacopaside I and underlying mechanism.
–Mechanisms, Efficacy, and Safety of Bacopa monnieri (Brahmi) for Cognitive and Brain Enhancement.
MEMORY:
–Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial.
–Bacopa monnieri ameliorates memory deficits in olfactory bulbectomized mice: possible involvement of glutamatergic and cholinergic systems.
–Chronic effects of Brahmi (Bacopa monnieri) on human memory.
ALZHEIMER'S DISEASE / DEMENTIA:
–Brahmi (Bacopa monnieri): An ayurvedic herb against the Alzheimer's disease.
–Use of Bacopa monnieri in the Treatment of Dementia Due to Alzheimer Disease: Systematic Review of Randomized Controlled Trials.
–Bacopa monnieri, a Neuroprotective Lead in Alzheimer Disease: A Review on Its Properties, Mechanisms of Action, and Preclinical and Clinical Studies.
–Bacopa monnieri as an Antioxidant Therapy to Reduce Oxidative Stress in the Aging Brain.
–Neurocognitive Effect of Nootropic Drug Brahmi (Bacopa monnieri) in Alzheimer's Disease.
–Bacopa monnieri prevents colchicine-induced dementia by anti-inflammatory action.
–Synergistic neuroprotection by phytocompounds of Bacopa monnieri in scopolamine-induced Alzheimer's disease mice model.
–Cognitive enhancement and neuroprotective effects of Bacopa monnieri in Alzheimer's disease model.
–Efficacy of Bacopa Monnieri (Brahmi) and Donepezil in Alzheimer's Disease and Mild Cognitive Impairment: A Randomized Double-Blind Parallel Phase 2b Study.
–Amelioration of Amyloid-β Induced Alzheimer's Disease by Bacopa monnieri through Modulation of Mitochondrial Dysfunction and GSK-3β/Wnt/β-Catenin Signaling.
–A Computational Study of Natural Compounds from Bacopa monnieri in the Treatment of Alzheimer's Disease.
–Neuroprotective effects of Bacopa monnieri in experimental model of dementia.
PARKINSON'S DISEASE:
–Bacopa monnieri in Patients with Parkinson's Disease: A Pilot Study.
–A Comprehensive Review on Preclinical Evidence-based Neuroprotective Potential of Bacopa monnieri against Parkinson's Disease.
–Neuroprotective effects of Bacopa monnieri in Parkinson's disease model.
–Anti-Parkinsonian effects of Bacopa monnieri: insights from transgenic and pharmacological Caenorhabditis elegans models of Parkinson's disease.
–Neuroprotective and Neurorescue Mode of Action of Bacopa monnieri (L.) Wettst in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Induced Parkinson's Disease: An In Silico and In Vivo Study.
DIABETES:
–Antihyperglycemic activity of bacosine, a triterpene from Bacopa monnieri, in alloxan-induced diabetic rats.
OPIOID TOXICITY:
–Beneficial effects of Bacopa monnieri extract on opioid induced toxicity.
–Neuroprotective effect of Bacopa monnieri against morphine-induced histopathological changes in the cerebellum of rats.
METHAMPHETAMINE TOXICITY:
–Bacopa Protects against Neurotoxicity Induced by MPP+ and Methamphetamine.
ULCERATIVE COLITIS:
–Exploring the ameliorative potential of Bacopa monnieri in acetic acid induced ulcerative colitis in mice.
RENOPROTECTIVE:
–Renoprotective effect of Bacopa monnieri via inhibition of advanced glycation end products and oxidative stress in STZ-nicotinamide-induced diabetic nephropathy.
CANCER:
–The Evolving Roles of Bacopa monnieri as Potential Anti-Cancer Agent: A Review.
–Advanced network pharmacology study reveals multi-pathway and multi-gene regulatory molecular mechanism of Bacopa monnieri in liver cancer based on data mining, molecular modeling, and microarray data analysis.
–Anticancer activity of Bacopa monnieri through apoptosis induction and mitophagy-dependent NLRP3 inflammasome inhibition in oral squamous cell carcinoma.
–Evaluation of anticancer potential of Bacopa monnieri L. against MCF-7 and MDA-MB 231 cell line.
–Chemopreventive and Anticancer Activities of Bacopa monnieri Extracted from Artificial Digestive Juices.
–The Purified Extract from the Medicinal Plant Bacopa monnieri, Bacopaside II, Inhibits Growth of Colon Cancer Cells In Vitro by Inducing Cell Cycle Arrest and Apoptosis.
–Cytotoxic and anti -tumour properties of ethanolic extract of bacopa monnieri (L) penn.