TRADITIONAL INTERNAL MEDICINE – DISEASES & FORMULAS

Gangrene

Gangrene is the death of body tissue (necrosis) caused by a severe lack of blood supply (ischemia) or serious bacterial infection.

There are several types of Gangrene:

  • Dry Gangrene: where blood supply to tissue is cut off, causing the area to turn brown to blackish-blue, dry up, and shrink.
  • Wet Gangrene: when bacterial infections infect the tissue, causing swelling and pus and a foul smell. It often spreads quickly.
  • Gas Gangrene: dangerous type caused by Clostridium bacteria that produces gas within tissues, usually associated with deep wound infections.
  • Internal Gangrene: Occurs when blood flow to an internal organ (e.g., appendix, gallbladder, intestines) is blocked.
  • Necrotizing Fasciitis: A rapidly spreading infection that destroys the tissue under the skin

Causes & Risk Factors

  • Diabetes: high blood sugar damages capillaries
  • Vascular Disease: Atherosclerosis (hardened arteries) and peripheral arterial disease restrict blood flow
  • Serious Trauma: Trauma, or Bruising that allows infection to enter
  • Smoking: hinders circulation

Modern Medical treatment includes Antibiotics (in case of infection), Surgery (to remove damaged tissue or restore circulation), and in serious cases, amputation.


Western Tradition

Internal Use
Decoction Liberans
Tincture of Myrrh
Tincture of Myrrh and Aloes

Topical application
Wormwood
Camomile
Black Nightshade
Aloe
Myrrh
Blessed Thistle
Niter
Verdigris

1. “Spirit of Wine has a notable Balsamic faculty, and powerfully resists Putrefaction, though but outwardly applied, it has been found of late one of the Potentest Remedies against Gangrenes”. (Boyle, out of Salmon)

Tincture of Myrrh
Tincture of Myrrh and Aloes

Chinese Classification

Qi Deficiency
Bu Zhong Yi Qi Tang
Huang Qi Jian Zhong Tang

Blood Deficiency with Cold
Dang Gui Si NI Tang

Coldness Obstructing Circulation
Wu Mei Wan

Blood Stasis with Toxicity
Mi Miao Yong An Tang

Pulmonary Gangrene from Phlegm and Heat
Jie Geng Tang (Platycodon Jie Geng + Licorice)
Da Qing Long Tang


Special Formulas

DECOCTION FOR GANGRENE
(Pharmacopee Usuelle, Louvain, 1821)
    Horehound
    Pennyroyal
    Rue
    Rosemary
    Sage
    Scordium                        1 part ea.
    Camomile
    Rose
    Elder                                2 parts ea.
    Marshmallow                 6 parts
    Fenugreek                      8 parts
    Linseed                          24 parts

DECOCTION FOR GANGRENE
(Dispensatorium medico pharmaceuticum Palatinatus, 1764)
    Yarrow
    Wormwood                    6 drams ea.
    Scordium
    Sage
    Hyssop
    Rue
    Elder flower
    St. Johns wort                ½ oz. ea.
    Rose                                 1 oz.
    Myrrh                               6 drams
    Aloes
    Asafetida                        ½ oz. ea.
Either of these can be decocted in 5 parts water and 2 parts vinegar and are applied with a flannel, changing regularly. A little Camphorated Spirit can be added to make it stronger.

POWDER FOR GANGRENE
    Unslaked Lime                3 parts
    Arsenic                              1 part
Make a paste with strong vinegar, form pills and dry in the sun. Powder and sprinkle over the Gangrene. (Syrian “Book of Medicine“)

SPIRIT FOR GANGRENE
    Mastic
    Myrrh
    Frankincense
    Amber                               2 oz. each
    Rectified Spirit of Wine  2 lbs.
Distill off the spirit for topical application. (Gazophylacium Medico-Physicum, Woyts, 1746)

Qi Deficiency
HUANG QI JIAN ZHONG TANG
    Maltose (Yi Tang)                     30 grams
    Cinnamon twig (Gui Zhi)          9 grams
    Paeonia (Bai Shao)                   18 grams
    Fried Licorice (Zhi Gan Cao)    6 grams
    Fresh Ginger (Sheng Jiang)     9 grams
    Jujube (Da Zao)                         4 pieces
    Astragalus (Huang Qi)             12 grams

Blood Stasis with Toxicity
SI MIAO YONG AN TANG
    Honeysuckle (Jin Yin Hua)
    Scrophularia (Xuan Shen)
    Dang Gui                                    9 grams ea.
Cyathula Niu Xi is often added for Gangrene of the Fingers or Toes


Research:

1. Systematic review and meta-analysis of Jueyin disease theory in the treatment of gangrene with traditional Chinese medicine formulations

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