Adhatoda vasica, Malabar nut

Vasa, Vasaka, Adarushah (Ayurveda)
Adathodai (Siddha)
Ba Sha Ka  བ་ཤ་ཀ  (Tibetan)
Arusa, Hashees-tussual (Unani)
Da Bo Gu (TCM)

Adhatoda vasica
Weinmann, Phytanthoza iconographia, 1739

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Botanical name:
Adhatoda vasica (syn. Justicia adhatoda)

Parts used:
Leaf, Flower, Root-bark

Temperature & Taste:
Cold, dry. Bitter

Uses:
1. Clears Phlegm and Heat, Stops Cough: (leaf, flower) (Ayurveda, Siddha, Unani)
-Cough, Bronchitis

2. Clears Heat, Stops Bleeding:
-Bleeding

3. Moves the Blood, Clears Stasis, Eases Pain: (TCM, Tibet)

4. Clears Heat and Toxin:
-Fever, Sore Throat

5. Clears Damp, Promotes Urine
-Edema, fluid retention

Dose:
Flower in Powder: 500mg–1 gram;
Leaf in Powder: 500mg–2 grams;
Root-bark in Powder: 250–500mg

Correctives:
 ... available in PRO version

Substitute:
 ... available in PRO version

Main Combinations:
1. Cough, Asthma, Fever, Adhatoda with  ... available in PRO version
2. Asthma:
i. Adhatoda leaf,  ... available in PRO version
ii. Adhatoda with  ... available in PRO version
iii. Adhatoda with  ... available in PRO version
iv. Adhatoda with  ... available in PRO version
v. Adhatoda with  ... available in PRO version
vi. Adhatoda with  ... available in PRO version
vii. Adhatoda with  ... available in PRO version
3. Tuberculosis, Adhatoda with  ... available in PRO version
4. Bleeding from Heat:
i. Adhatoda with  ... available in PRO version
ii. Uterine Bleeding, Adhatoda with  ... available in PRO version
5. Gastric Ulcers, Adhatoda,  ... available in PRO version
6. Fever, Adhatoda with  ... available in PRO version
7. Chronic Fever, Adhatoda with  ... available in PRO version
8. Skin diseases:
i. Adhatoda with  ... available in PRO version
ii. Adhatoda with  ... available in PRO version

Major Formulas:
Kanakasava

Cautions:
1. Not used in Pregnancy (except during delivery)
2. Not used in Vata (Wind) conditions
3. It is a strong medicine, so avoid overdose. Overdose may cause vomiting, diarrhea and hypotension.

Main Preparations used:

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• Extra Info
  
• Research

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(Last updated 9/2018)

1. ANTI-BACTERIAL:
–Antimicrobial, antioxidant, and cytotoxic properties of vasicine acetate synthesized from vasicine isolated from Adhatoda vasica L.
–Anti-inflammatory and antimicrobial properties of pyrroloquinazoline alkaloids from Adhatoda vasica Nees.
–Enzyme inhibition, antioxidant and antibacterial potential of vasicine isolated from Adhatoda vasica Nees.

2. ANTI-MYCOBACTERIAL:
–Activity of bromhexine and ambroxol, semi-synthetic derivatives of vasicine from the Indian shrub Adhatoda vasica, against Mycobacterium tuberculosis in vitro.
–Antimycobacterial activity of two natural alkaloids, vasicine acetate and 2-acetyl benzylamine, isolated from Indian shrub Adhatoda vasica Ness. leaves.
–Antitubercular effect of an extract of Adhatoda vasica.
–Anti-tubercular action of Adhatoda vasica (N.O. acanthacea).

3. MULTI-DRUG RESISTANT TUBERCULOSIS:
–Anti-tuberculosis activity of selected medicinal plants against multi-drug resistant Mycobacterium tuberculosis isolates.

4. ANTIOXIDANT:
–Antimicrobial, antioxidant, and cytotoxic properties of vasicine acetate synthesized from vasicine isolated from Adhatoda vasica L.
–Enzyme inhibition, antioxidant and antibacterial potential of vasicine isolated from Adhatoda vasica Nees.

5. ANTI-INFLAMMATORY:
–Anti-inflammatory and antimicrobial properties of pyrroloquinazoline alkaloids from Adhatoda vasica Nees.
–Study of alkaloids from Adhatoda vasica Nees on their antiinflammatory activity.

6. CYTOTOXIC:
–Antimicrobial, antioxidant, and cytotoxic properties of vasicine acetate synthesized from vasicine isolated from Adhatoda vasica L.

7. HEPATOPROTECTIVE:
–Hepatoprotective activity of Adhatoda vasica aqueous leaf extract on D-galactosamine-induced liver damage in rats.

8. RADIO-PROTECTIVE:
–Protective effect of Adhatoda vascia Nees against radiation-induced damage at cellular, biochemical and chromosomal levels in Swiss albino mice.
–Modulatory influence of Adhatoda vasica Nees leaf extract against gamma irradiation in Swiss albino mice.

9. ANTI-ULCER:
–Anti-ulcer activity of Adhatoda vasica Nees.

10. ANTI-ALLERGIC:
–Search for new plant constituents with potential antiphlogistic and antiallergic activity.

11. ANTI-TUSSIVE:
–Antitussive effect of Adhatoda vasica extract on mechanical or chemical stimulation-induced coughing in animals.

12. BRONCHODILATOR:
–A bronchodilator alkaloid (vasicinone) from Adhatoda vasica Nees.

13. ANTI-ASTHMATIC:
–A clinical review of different formulations of Vasa (Adhatoda vasica) on Tamaka Shwasa (asthma).

14. ANTI-ALZHEIMER
–In-vitro evaluation of selected Egyptian traditional herbal medicines for treatment of Alzheimer disease.

15. ANTI-IMPLANTATION / ABORTIFACIENT:
–Anti-implantation activity of some indigenous plants in rats.
–Vasicine, alkaloid of Adhatoda vasica, a promising uterotonic abortifacient.