Trichosanthes Fructus, Gua Lou 瓜蒌
Gua Lou (TCM)
Trichosanthes kirilowii flower (left), fruit (right)
(Photos by 杉山龍彦) (Left: Wikimedia; Right: Wikimedia)
(Photos by 杉山龍彦) (Left: Wikimedia; Right: Wikimedia)
Botanical name:
Trichosanthes kirilowii (syn. T. japonica), T. rosthornii (syn. T. uniflora)
Parts used:
Fruit
Temperature & Taste:
Cold, Moist. Sweet
Classification:
P. Clear Phlegm
Trichosanthes kirilowii (syn. T. japonica), T. rosthornii (syn. T. uniflora)
Parts used:
Fruit
Temperature & Taste:
Cold, Moist. Sweet
Classification:
P. Clear Phlegm
Uses:
1. Moistens the Lungs, Clears Phlegm-Heat:
-Cough with yellow, hard-to-clear sputum
2. Moves Qi, Opens the Chest:
-pressure, a stifling feeling, constriction or pain in the chest and diaphragm
3. Clears Pus, Resolves Abscesses:
-Abscess of the Lungs, Breast or Intestines
DOSE:
9–20 grams in Decoction
9–20 grams in Decoction
Main Combinations:
1. Cough from Hot-Phlegm:
i. with hard-to-clear sputum, with Fritillaria Zhe Bei Mu and Platycodon Jie Geng.
ii. with focal distention in the chest and abdomen with Pinellia Ban Xia and Citrus Chen Pi
2. Painful Chest obstruction with Pinellia Ban Xia and Garlic Chive (Allium macrostemi, Xie Bai)
3. Abscess:
i. early stage Breast Abscess, with Dandelion (Pu Gong Ying) and Frankincense (Ru Xiang)
ii. Lung Abscess (and other abscess) with Myrrh and Frankincense
iii. Intestinal (or other) Abscess with Heat and Toxin and Deficiency, with Lonicera Jin Yin Hua, Forsythia Lian Qiao, Astragalus Huang Qi (as in Expel Pus Powder [Pai Nong San])
Cautions:
1. Not used for Diarrhea from Stomach and Spleen weakness.
DRUG INTERACTION:
1. Not used with Aconite species (counteracts); Incompatible with Ginger and Achyranthes Niu Xi.
Main Preparations used:
1. Not used for Diarrhea from Stomach and Spleen weakness.
DRUG INTERACTION:
1. Not used with Aconite species (counteracts); Incompatible with Ginger and Achyranthes Niu Xi.
Main Preparations used:
Click the Tabs above for more information on this Medicine
GENERAL / REVIEW
–Trichosanthis Fructus: botany, traditional uses, phytochemistry and pharmacology.
COMBINATIONS
–[Use of Trichosanthis fructus and the core drug pair Trichosanthis fructus-Glycyrrhizae radix et rhizoma in traditional Chinese prescriptions: molecular mechanisms in network pharmacology and molecular docking].
–[Study on effect of "Trichosanthis Fructus-Allii Macrostemonis Bulbus" on atherosclerosis in ApoE~(-/-) mice based on liver metabonomics].
–[Toxic effects of combination of Aconiti Lateralis Radix Praeparata with Trichosanthis Fructus on inflammatory response and myocardial fibrosis in pressure overload rats based on β2-AR/PKA signal].
PROCESSING
–[Study on HPLC Fingerprint of Trichosanthes Fruit and Its Processed Products].
ANTI-PLATELET / ANTI-THROMBOTIC
–[Anti-platelet aggregation and anti-thrombotic mechanism of Trichosanthis Fructus combined with aspirin based on network pharmacology].
CANCER
–The methylene chloride fraction of Trichosanthis Fructus induces apoptosis in U937 cells through the mitochondrial pathway.
–Trichosanthis Fructus: botany, traditional uses, phytochemistry and pharmacology.
COMBINATIONS
–[Use of Trichosanthis fructus and the core drug pair Trichosanthis fructus-Glycyrrhizae radix et rhizoma in traditional Chinese prescriptions: molecular mechanisms in network pharmacology and molecular docking].
–[Study on effect of "Trichosanthis Fructus-Allii Macrostemonis Bulbus" on atherosclerosis in ApoE~(-/-) mice based on liver metabonomics].
–[Toxic effects of combination of Aconiti Lateralis Radix Praeparata with Trichosanthis Fructus on inflammatory response and myocardial fibrosis in pressure overload rats based on β2-AR/PKA signal].
PROCESSING
–[Study on HPLC Fingerprint of Trichosanthes Fruit and Its Processed Products].
ANTI-PLATELET / ANTI-THROMBOTIC
–[Anti-platelet aggregation and anti-thrombotic mechanism of Trichosanthis Fructus combined with aspirin based on network pharmacology].
CANCER
–The methylene chloride fraction of Trichosanthis Fructus induces apoptosis in U937 cells through the mitochondrial pathway.